Sodium Valproate
Also known as: Epilim, Depakote, Valproic acid
What it's for
Sodium valproate prevents seizures in epilepsy and stabilises mood in bipolar disorder. It works by calming electrical activity in the brain.
Comes as: Tablets, capsules, liquid, or modified-release
How to take it
- Dose varies depending on the condition.
- Usually taken once or twice daily.
- Modified-release can be taken once daily.
- Take with or after food to reduce stomach upset.
Doses here are typical. Always follow the instructions from your prescriber or on the packet — they come first.
Common side effects
- Weight gain
- Feeling sick or stomach pain
- Tremor
- Drowsiness
- Hair thinning (temporary)
The leaflet inside the packet lists all known side effects.
Important safety points
- MUST NOT be taken during pregnancy - causes serious birth defects
- Women of childbearing age need a pregnancy prevention programme
- Tell your doctor about all medicines you take
- Regular blood tests may be needed
Get medical help urgently if…
- You could be pregnant - contact your doctor immediately
- You have yellowing of your skin or eyes
- You have severe stomach pain or vomiting
- You have unusual bruising or bleeding
Call NHS 111 for urgent advice, or 999 if someone is seriously unwell.
Before you act on anything here
This page is general information, written to help you understand — it is not personal medical advice and it cannot tell you what is right for you. Talk to your own GP, pharmacist or nurse about your own health.
- Need help now but it's not an emergency? Call NHS 111 or use 111.nhs.uk.
- Emergency? Call 999 or go to A&E.